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Ergosta-7, 9 (11), 22-trien-3β-ol Interferes with LPS Docking to LBP, CD14, and TLR4/MD-2 Co-Receptors to Attenuate the NF-κB Inflammatory Pathway In Vitro and Drosophila

Ergosta-7, 9 (11), 22-trien-3β-ol (EK100) was isolated from Cordyceps militaris, which has been used as a traditional anti-inflammatory medicine. EK100 has been reported to attenuate inflammatory diseases, but its anti-inflammatory mechanism is still unclear. We were the first to investigate the eff...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Hsieh, Wen-Tsong, Hsu, Min-Hsien, Lin, Wen-Jen, Xiao, Yi-Cheng, Lyu, Ping-Chiang, Liu, Yi-Chung, Lin, Wei-Yong, Kuo, Yueh-Hsiung, Chung, Jing-Gung
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234490/
https://ncbi.nlm.nih.gov/pubmed/34204506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126511
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