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Phosphorylation of human phospholipase A1 DDHD1 at newly identified phosphosites affects its subcellular localization
Phospholipase A1 (PLA1) hydrolyzes the fatty acids of glycerophospholipids, which are structural components of the cellular membrane. Genetic mutations in DDHD1, an intracellular PLA1, result in hereditary spastic paraplegia (HSP) in humans. However, the regulation of DDHD1 activity has not yet been...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8234217/ https://ncbi.nlm.nih.gov/pubmed/34089703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100851 |
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