Phosphorylation of human phospholipase A1 DDHD1 at newly identified phosphosites affects its subcellular localization

Phospholipase A1 (PLA1) hydrolyzes the fatty acids of glycerophospholipids, which are structural components of the cellular membrane. Genetic mutations in DDHD1, an intracellular PLA1, result in hereditary spastic paraplegia (HSP) in humans. However, the regulation of DDHD1 activity has not yet been...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Matsumoto, Naoki, Nemoto-Sasaki, Yoko, Oka, Saori, Arai, Seisuke, Wada, Ikuo, Yamashita, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234217/
https://ncbi.nlm.nih.gov/pubmed/34089703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100851
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