Phosphorylation of human phospholipase A1 DDHD1 at newly identified phosphosites affects its subcellular localization

Phospholipase A1 (PLA1) hydrolyzes the fatty acids of glycerophospholipids, which are structural components of the cellular membrane. Genetic mutations in DDHD1, an intracellular PLA1, result in hereditary spastic paraplegia (HSP) in humans. However, the regulation of DDHD1 activity has not yet been...

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Spremljeno u:
Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Matsumoto, Naoki, Nemoto-Sasaki, Yoko, Oka, Saori, Arai, Seisuke, Wada, Ikuo, Yamashita, Atsushi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2021
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234217/
https://ncbi.nlm.nih.gov/pubmed/34089703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100851
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