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DNA-RNA Hybrid (R-Loop): From a Unified Picture of the Mammalian Telomere to the Genome-Wide Profile

Local three-stranded DNA/RNA hybrid regions of genomes (R-loops) have been detected either by binding of a monoclonal antibody (DRIP assay) or by enzymatic recognition by RNaseH. Such a structure has been postulated for mouse and human telomeres, clearly suggested by the identification of the comple...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Rassoulzadegan, Minoo, Sharifi-Zarchi, Ali, Kianmehr, Leila
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233970/
https://ncbi.nlm.nih.gov/pubmed/34205454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061556
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