A smart multiantenna gene theranostic system based on the programmed assembly of hypoxia-related siRNAs

The systemic therapeutic utilisation of RNA interference (RNAi) is limited by the non-specific off-target effects, which can have severe adverse impacts in clinical applications. The accurate use of RNAi requires tumour-specific on-demand conditional activation to eliminate the off-target effects of...

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Udgivet i:Nat Commun
Main Authors: Gong, Xue, Wang, Haizhou, Li, Ruomeng, Tan, Kaiyue, Wei, Jie, Wang, Jing, Hong, Chen, Shang, Jinhua, Liu, Xiaoqing, Liu, Jing, Wang, Fuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233311/
https://ncbi.nlm.nih.gov/pubmed/34172725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24191-9
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