The archaeal triphosphate tunnel metalloenzyme SaTTM defines structural determinants for the diverse activities in the CYTH protein family

CYTH proteins make up a large superfamily that is conserved in all three domains of life. These enzymes have a triphosphate tunnel metalloenzyme (TTM) fold, which typically results in phosphatase functions, e.g., RNA triphosphatase, inorganic polyphosphatase, or thiamine triphosphatase. Some CYTH or...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Vogt, Marian S., Ngouoko Nguepbeu, Roi R., Mohr, Michael K.F., Albers, Sonja-Verena, Essen, Lars-Oliver, Banerjee, Ankan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233210/
https://ncbi.nlm.nih.gov/pubmed/34029589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100820
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