Structure–function analysis of Plasmodium RNA triphosphatase and description of a triphosphate tunnel metalloenzyme superfamily that includes Cet1-like RNA triphosphatases and CYTH proteins

RNA triphosphatase catalyzes the first step in mRNA capping. The RNA triphosphatases of fungi and protozoa are structurally and mechanistically unrelated to the analogous mammalian enzyme, a situation that recommends RNA triphosphatase as an anti-infective target. Fungal and protozoan RNA triphospha...

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Bibliografiske detaljer
Main Authors: Gong, Chunling, Smith, Paul, Shuman, Stewart
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524888/
https://ncbi.nlm.nih.gov/pubmed/16809816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.119806
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