SIRT1-dependent restoration of NAD+ homeostasis after increased extracellular NAD+ exposure

In the last several years, NAD+ supplementation has emerged as an innovative and safe therapeutic strategy for a wide spectrum of disorders, including diabetes and neuropathy. However, critical questions remain as to how NAD+ and its precursors are taken up by cells, as well as the effects of long-l...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Buonvicino, Daniela, Ranieri, Giuseppe, Pittelli, Maria, Lapucci, Andrea, Bragliola, Stefania, Chiarugi, Alberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233143/
https://ncbi.nlm.nih.gov/pubmed/34097876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100855
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