Regulatory and Functional Involvement of Long Non-Coding RNAs in DNA Double-Strand Break Repair Mechanisms

Protection of genome integrity is vital for all living organisms, particularly when DNA double-strand breaks (DSBs) occur. Eukaryotes have developed two main pathways, namely Non-Homologous End Joining (NHEJ) and Homologous Recombination (HR), to repair DSBs. While most of the current research is fo...

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Dettagli Bibliografici
Pubblicato in:Cells
Autori principali: Papaspyropoulos, Angelos, Lagopati, Nefeli, Mourkioti, Ioanna, Angelopoulou, Andriani, Kyriazis, Spyridon, Liontos, Michalis, Gorgoulis, Vassilis, Kotsinas, Athanassios
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232683/
https://ncbi.nlm.nih.gov/pubmed/34203749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061506
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