Antimicrobial Activity of a Library of Thioxanthones and Their Potential as Efflux Pump Inhibitors

The overexpression of efflux pumps is one of the causes of multidrug resistance, which leads to the inefficacy of drugs. This plays a pivotal role in antimicrobial resistance, and the most notable pumps are the AcrAB-TolC system (AcrB belongs to the resistance-nodulation-division family) and the Nor...

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Foilsithe in:Pharmaceuticals (Basel)
Main Authors: Durães, Fernando, Palmeira, Andreia, Cruz, Bárbara, Freitas-Silva, Joana, Szemerédi, Nikoletta, Gales, Luís, da Costa, Paulo Martins, Remião, Fernando, Silva, Renata, Pinto, Madalena, Spengler, Gabriella, Sousa, Emília
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232621/
https://ncbi.nlm.nih.gov/pubmed/34203998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14060572
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