Circulating Tumor DNA Predicts Pathologic and Clinical Outcomes Following Neoadjuvant Chemoradiation and Surgery for Patients With Locally Advanced Rectal Cancer

PURPOSE: This study was designed to assess the ability of perioperative circulating tumor DNA (ctDNA) to predict surgical outcome and recurrence following neoadjuvant chemoradiation for locally advanced rectal cancer (LARC). MATERIALS AND METHODS: Twenty-nine patients with newly diagnosed LARC treat...

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Publicat a:JCO Precis Oncol
Autors principals: McDuff, Susan G. R., Hardiman, Karin M., Ulintz, Peter J., Parikh, Aparna R., Zheng, Hui, Kim, Daniel W., Lennerz, Jochen K., Hazar-Rethinam, Mehlika, Van Seventer, Emily E., Fetter, Isobel J., Nadres, Brandon, Eyler, Christine E., Ryan, David P., Weekes, Colin D., Clark, Jeffrey W., Cusack, James C., Goyal, Lipika, Zhu, Andrew X., Wo, Jennifer Y., Blaszkowsky, Lawrence S., Allen, Jill, Corcoran, Ryan B., Hong, Theodore S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2021
Matèries:
ORIGINAL REPORTS
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232395/
https://ncbi.nlm.nih.gov/pubmed/34250394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.20.00220
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