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Quality by Design Methodology Applied to Process Optimization and Scale up of Curcumin Nanoemulsions Produced by Catastrophic Phase Inversion

In the presented study, we report development of a stable, scalable, and high-quality curcumin-loaded oil/water (o/w) nanoemulsion manufactured by concentration-mediated catastrophic phase inversion as a low energy nanoemulsification strategy. A design of experiments (DoE) was constructed to determi...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Adena, Sandeep Kumar Reddy, Herneisey, Michele, Pierce, Eric, Hartmeier, Paul R., Adlakha, Suneera, Hosfeld, Marco A. I., Drennen, James K., Janjic, Jelena M.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232217/
https://ncbi.nlm.nih.gov/pubmed/34203672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060880
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