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Reversing donor-specific antibody responses and antibody-mediated rejection with bortezomib and belatacept in mice and kidney transplant recipients

Active antibody-mediated rejection (AMR) is a potentially devastating complication and consistently effective treatment remains elusive. We hypothesized that the reversal of acute AMR requires rapid elimination of antibody-secreting plasma cells (PC) with a proteasome inhibitor, bortezomib, followed...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Transplant
Egile Nagusiak: Jain, Dharmendra, Rajab, Amer, Young, James S, Yin, Dengping, Nadasdy, Tibor, Chong, Anita S, Pelletier, Ronald P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232017/
https://ncbi.nlm.nih.gov/pubmed/32243663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15881
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