Rapid Reduction in Donor-Specific Anti-Human Leukocyte Antigen Antibodies and Reversal of Antibody-Mediated Rejection With Bortezomib in Pediatric Heart Transplant Patients

BACKGROUND: High titer donor-specific antibodies (DSA) and positive crossmatch in cardiac transplant recipients is associated with increased mortality from antibody-mediated rejection (AMR). Although treatment to reduce antihuman leukocyte antigen antibodies using plasmapheresis, intravenous immunog...

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Main Authors: Morrow, William Robert, Frazier, Elizabeth A., Mahle, William T., Harville, Terry O., Pye, Sherry E., Knecht, Kenneth R., Howard, Emily L., Smith, R. Neal, Saylors, Robert L., Garcia, Xiomara, Jaquiss, Robert D.B., Woodle, E. Steve
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730122/
https://ncbi.nlm.nih.gov/pubmed/22179403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31823f7eea
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