Učitavanje...

Association between Predicted Effects of TP53 Missense Variants on Protein Conformation and Their Phenotypic Presentation as Li-Fraumeni Syndrome or Hereditary Breast Cancer

Rare germline pathogenic TP53 missense variants often predispose to a wide spectrum of tumors characterized by Li-Fraumeni syndrome (LFS) but a subset of variants is also seen in families with exclusively hereditary breast cancer (HBC) outcomes. We have developed a logistic regression model with the...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Liu, Yaxuan, Axell, Olga, van Leeuwen, Tom, Konrat, Robert, Kharaziha, Pedram, Larsson, Catharina, Wright, Anthony P. H., Bajalica-Lagercrantz, Svetlana
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231809/
https://ncbi.nlm.nih.gov/pubmed/34198491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126345
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!