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A Biophysical Insight of Camptothecin Biodistribution: Towards a Molecular Understanding of Its Pharmacokinetic Issues

Camptothecin (CPT) is a potent anticancer drug, and its putative oral administration is envisioned although difficult due to physiological barriers that must be overcome. A comprehensive biophysical analysis of CPT interaction with biointerface models can be used to predict some pharmacokinetic issu...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Almeida, Andreia, Fernandes, Eduarda, Sarmento, Bruno, Lúcio, Marlene
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231504/
https://ncbi.nlm.nih.gov/pubmed/34204692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060869
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