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A Deep-Learning Sequence-Based Method to Predict Protein Stability Changes Upon Genetic Variations

Several studies have linked disruptions of protein stability and its normal functions to disease. Therefore, during the last few decades, many tools have been developed to predict the free energy changes upon protein residue variations. Most of these methods require both sequence and structure infor...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Genes (Basel)
Main Authors: Pancotti, Corrado, Benevenuta, Silvia, Repetto, Valeria, Birolo, Giovanni, Capriotti, Emidio, Sanavia, Tiziana, Fariselli, Piero
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231498/
https://ncbi.nlm.nih.gov/pubmed/34204764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060911
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