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A Deep-Learning Sequence-Based Method to Predict Protein Stability Changes Upon Genetic Variations

Several studies have linked disruptions of protein stability and its normal functions to disease. Therefore, during the last few decades, many tools have been developed to predict the free energy changes upon protein residue variations. Most of these methods require both sequence and structure infor...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Pancotti, Corrado, Benevenuta, Silvia, Repetto, Valeria, Birolo, Giovanni, Capriotti, Emidio, Sanavia, Tiziana, Fariselli, Piero
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231498/
https://ncbi.nlm.nih.gov/pubmed/34204764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060911
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