Surfactant-Assisted Distal Pulmonary Distribution of Budesonide Revealed by Mass Spectrometry Imaging

Direct lung administration of budesonide in combination with surfactant reduces the incidence of bronchopulmonary dysplasia. Although the therapy is currently undergoing clinical development, the lung distribution of budesonide throughout the premature neonatal lung has not yet been investigated. He...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Zecchi, Riccardo, Franceschi, Pietro, Tigli, Laura, Pioselli, Barbara, Mileo, Valentina, Murgia, Xabier, Salomone, Fabrizio, Pieraccini, Giuseppe, Usada, Haruo, Schmidt, Augusto F., Hillman, Noah H., Kemp, Matthew W., Jobe, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231273/
https://ncbi.nlm.nih.gov/pubmed/34204670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060868
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