Optimization of Tabersonine Methoxylation to Increase Vindoline Precursor Synthesis in Yeast Cell Factories

Plant specialized metabolites are widely used in the pharmaceutical industry, including the monoterpene indole alkaloids (MIAs) vinblastine and vincristine, which both display anticancer activity. Both compounds can be obtained through the chemical condensation of their precursors vindoline and cath...

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Publicat a:Molecules
Autors principals: Lemos Cruz, Pamela, Kulagina, Natalja, Guirimand, Grégory, De Craene, Johan-Owen, Besseau, Sébastien, Lanoue, Arnaud, Oudin, Audrey, Giglioli-Guivarc’h, Nathalie, Papon, Nicolas, Clastre, Marc, Courdavault, Vincent
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231165/
https://ncbi.nlm.nih.gov/pubmed/34208368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123596
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