Optimization of Tabersonine Methoxylation to Increase Vindoline Precursor Synthesis in Yeast Cell Factories

Plant specialized metabolites are widely used in the pharmaceutical industry, including the monoterpene indole alkaloids (MIAs) vinblastine and vincristine, which both display anticancer activity. Both compounds can be obtained through the chemical condensation of their precursors vindoline and cath...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lemos Cruz, Pamela, Kulagina, Natalja, Guirimand, Grégory, De Craene, Johan-Owen, Besseau, Sébastien, Lanoue, Arnaud, Oudin, Audrey, Giglioli-Guivarc’h, Nathalie, Papon, Nicolas, Clastre, Marc, Courdavault, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231165/
https://ncbi.nlm.nih.gov/pubmed/34208368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123596
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