Modulation of Glutamate Transporter EAAT1 and Inward-Rectifier Potassium Channel K(ir4.1) Expression in Cultured Spinal Cord Astrocytes by Platinum-Based Chemotherapeutics

Platinum-based chemotherapeutics still play an essential role in cancer treatment. Despite their high effectiveness, severe side effects such as chemotherapy-induced neuropathy (CIPN) occur frequently. The pathophysiology of CIPN by platinum-based chemotherapeutics is not fully understood yet, but p...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Leo, Markus, Schmitt, Linda-Isabell, Steffen, Rebecca, Kutritz, Andrea, Kleinschnitz, Christoph, Hagenacker, Tim
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230757/
https://ncbi.nlm.nih.gov/pubmed/34208258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126300
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