MPLA and AddaVax(®) Adjuvants Fail to Promote Intramuscular LaAg Vaccine Protectiveness against Experimental Cutaneous Leishmaniasis

There is so far no vaccine approved for human leishmaniasis, mainly because of the lack of appropriate adjuvants. This study aimed to evaluate in mice the capacity of a mixture of monophosphoryl lipid A (MPLA) and AddaVax(®) adjuvants in enhancing the efficacy of a Leishvacin(®)-like vaccine compris...

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Publicat a:Microorganisms
Autors principals: Oliveira-Maciel, Diogo, dos-Santos, Júlio Souza, Oliveira-Silva, Gabriel, de Mello, Mirian França, da Fonseca-Martins, Alessandra Marcia, Carneiro, Monique Pacheco Duarte, Ramos, Tadeu Diniz, Firmino-Cruz, Luan, Gomes, Daniel Claudio Oliveira, Rossi-Bergmann, Bartira, de Matos Guedes, Herbert Leonel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230739/
https://ncbi.nlm.nih.gov/pubmed/34207948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9061272
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