Adjuvanted Schistosoma mansoni-Cathepsin B With Sulfated Lactosyl Archaeol Archaeosomes or AddaVax™ Provides Protection in a Pre-Clinical Schistosomiasis Model

Schistosomiasis threatens 800 million people worldwide. Chronic pathology manifests as hepatosplenomegaly, and intestinal schistosomiasis caused by Schistosoma mansoni can lead to liver fibrosis, cirrhosis, and blood in the stool. To assist the only FDA-approved drug, praziquantel, in parasite elimi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Perera, Dilhan J., Hassan, Adam S., Jia, Yimei, Ricciardi, Alessandra, McCluskie, Michael J., Weeratna, Risini D., Ndao, Momar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701121/
https://ncbi.nlm.nih.gov/pubmed/33304354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.605288
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