Adjuvanted Schistosoma mansoni-Cathepsin B With Sulfated Lactosyl Archaeol Archaeosomes or AddaVax™ Provides Protection in a Pre-Clinical Schistosomiasis Model

Schistosomiasis threatens 800 million people worldwide. Chronic pathology manifests as hepatosplenomegaly, and intestinal schistosomiasis caused by Schistosoma mansoni can lead to liver fibrosis, cirrhosis, and blood in the stool. To assist the only FDA-approved drug, praziquantel, in parasite elimi...

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發表在:Front Immunol
Main Authors: Perera, Dilhan J., Hassan, Adam S., Jia, Yimei, Ricciardi, Alessandra, McCluskie, Michael J., Weeratna, Risini D., Ndao, Momar
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701121/
https://ncbi.nlm.nih.gov/pubmed/33304354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.605288
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