Crystallography, Molecular Modeling, and COX-2 Inhibition Studies on Indolizine Derivatives

The cyclooxygenase-2 (COX-2) enzyme is an important target for drug discovery and development of novel anti-inflammatory agents. Selective COX-2 inhibitors have the advantage of reduced side-effects, which result from COX-1 inhibition that is usually observed with nonselective COX inhibitors. In thi...

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Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Venugopala, Katharigatta N., Chandrashekharappa, Sandeep, Tratrat, Christophe, Deb, Pran Kishore, Nagdeve, Rahul D., Nayak, Susanta K., Morsy, Mohamed A., Borah, Pobitra, Mahomoodally, Fawzi M., Mailavaram, Raghu Prasad, Attimarad, Mahesh, Aldhubiab, Bandar E., Sreeharsha, Nagaraja, Nair, Anroop B., Alwassil, Osama I., Haroun, Michelyne, Mohanlall, Viresh, Shinu, Pottathil, Venugopala, Rashmi, Kandeel, Mahmoud, Nandeshwarappa, Belakatte P., Ibrahim, Yasmine F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230391/
https://ncbi.nlm.nih.gov/pubmed/34200764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123550
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