Impact of TSPO Receptor Polymorphism on [(18)F]GE-180 Binding in Healthy Brain and Pseudo-Reference Regions of Neurooncological and Neurodegenerative Disorders

TSPO-PET tracers are sensitive to a single-nucleotide polymorphism (rs6971-SNP), resulting in low-, medium- and high-affinity binders (LABs, MABs and HABS), but the clinical relevance of [(18)F]GE-180 is still unclear. We evaluated the impact of rs6971-SNP on in vivo [(18)F]GE-180 binding in a healt...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Life (Basel)
Main Authors: Vettermann, Franziska J., Harris, Stefanie, Schmitt, Julia, Unterrainer, Marcus, Lindner, Simon, Rauchmann, Boris-Stephan, Palleis, Carla, Weidinger, Endy, Beyer, Leonie, Eckenweber, Florian, Schuster, Sebastian, Biechele, Gloria, Ferschmann, Christian, Milenkovic, Vladimir M., Wetzel, Christian H., Rupprecht, Rainer, Janowitz, Daniel, Buerger, Katharina, Perneczky, Robert, Höglinger, Günter U., Levin, Johannes, Haass, Christian, Tonn, Joerg C., Niyazi, Maximilian, Bartenstein, Peter, Albert, Nathalie L., Brendel, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229996/
https://ncbi.nlm.nih.gov/pubmed/34073557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life11060484
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares