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Insufficient Anthrax Lethal Toxin Neutralization Is Associated with Antibody Subclass and Domain Specificity in the Plasma of Anthrax-Vaccinated Individuals

Anthrax vaccine adsorbed (AVA) is a significant line of defense against bioterrorist attack from Bacillus anthracis spores. However, in a subset of individuals, this vaccine may produce a suboptimal quantity of anti-protective antigen (PA), antibodies that are poorly neutralizing, and/or antibody ti...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Smith, Kenneth, Garman, Lori, Norris, Kathleen, Muther, Jennifer, Duke, Angie, Engler, Renata J. M., Nelson, Michael R., Collins, Limone C., Spooner, Christina, Guthridge, Carla, James, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229884/
https://ncbi.nlm.nih.gov/pubmed/34199431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9061204
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