Erythropoietin Gene Therapy Delays Retinal Degeneration Resulting from Oxidative Stress in the Retinal Pigment Epithelium

Erythropoietin (EPO) plays an important role in erythropoiesis by its action in blocking apoptosis of progenitor cells and protects both photoreceptors and retinal ganglion cells from induced or inherited degeneration. A modified form of EPO, EPO-R76E has attenuated erythropoietic activity but is ef...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antioxidants (Basel)
Main Authors: Biswal, Manas R., Wang, Zhaoyao, Paulson, Ryan J., Uddin, Rukshana R., Tong, Yao, Zhu, Ping, Li, Hong, Lewin, Alfred S.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229633/
https://ncbi.nlm.nih.gov/pubmed/34070383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10060842
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