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Erythropoietin Gene Therapy Delays Retinal Degeneration Resulting from Oxidative Stress in the Retinal Pigment Epithelium

Erythropoietin (EPO) plays an important role in erythropoiesis by its action in blocking apoptosis of progenitor cells and protects both photoreceptors and retinal ganglion cells from induced or inherited degeneration. A modified form of EPO, EPO-R76E has attenuated erythropoietic activity but is ef...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Biswal, Manas R., Wang, Zhaoyao, Paulson, Ryan J., Uddin, Rukshana R., Tong, Yao, Zhu, Ping, Li, Hong, Lewin, Alfred S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229633/
https://ncbi.nlm.nih.gov/pubmed/34070383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10060842
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