RET Regulates Human Medullary Thyroid Cancer Cell Proliferation through CDK5 and STAT3 Activation

Medullary thyroid cancer (MTC) is a neuroendocrine tumor that arises from the parafollicular C-cells, which produces the hormone calcitonin. RET is a transmembrane receptor protein-tyrosine kinase, which is highly expressed in MTC. Our previous studies reported that cyclin-dependent kinase 5 (CDK5)...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Yue, Chia-Herng, Oner, Muhammet, Chiu, Chih-Yuan, Chen, Mei-Chih, Teng, Chieh-Lin, Wang, Hsin-Yi, Hsieh, Jer-Tsong, Lai, Chih-Ho, Lin, Ho
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229599/
https://ncbi.nlm.nih.gov/pubmed/34207842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060860
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