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Effects of Hyperhomocysteinemia on the Platelet-Driven Contraction of Blood Clots

Hyperhomocysteinemia (HHcy) is associated with thrombosis, but the mechanistic links between them are not understood. We studied effects of homocysteine (Hcy) on clot contraction in vitro and in a rat model of HHcy. Incubation of blood with exogenous Hcy for 1 min enhanced clot contraction, while 15...

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Publicado en:Metabolites
Main Authors: Litvinov, Rustem I., Peshkova, Alina D., Le Minh, Giang, Khaertdinov, Nail N., Evtugina, Natalia G., Sitdikova, Guzel F., Weisel, John W.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228611/
https://ncbi.nlm.nih.gov/pubmed/34205914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11060354
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