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Quantitative structural mechanobiology of platelet-driven blood clot contraction

Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets. A key elementary step of contraction is sequential extension–retraction of platelet filop...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Oleg V., Litvinov, Rustem I., Alber, Mark S., Weisel, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668372/
https://ncbi.nlm.nih.gov/pubmed/29097692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00885-x
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