Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways

PURPOSE: To delineate recurrent oncogenic driver alterations and dysregulated pathways in esophageal adenocarcinoma and to assess their prognostic value. EXPERIMENTAL DESIGN: We analyzed a large cohort of patients with lower esophageal and junctional adenocarcinoma, prospectively sequenced by MSK-IM...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Clin Cancer Res
Κύριοι συγγραφείς: Sihag, Smita, Nussenzweig, Samuel C., Walch, Henry S., Hsu, Meier, See Tan, Kay, Sanchez Vega, Francisco, Chatila, Walid K., De La Torre, Sergio, Patel, Assem, Janjigian, Yelena Y., Maron, Steven, Ku, Geoffrey Y., Tang, Laura H., Hechtman, Jaclyn, Shah, Pari M., Wu, Abraham, Jones, David R., Molena, Daniela, Solit, David B., Schultz, Nikolaus, Berger, Michael F.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2021
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228505/
https://ncbi.nlm.nih.gov/pubmed/33795256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-4707
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