Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways

PURPOSE: To delineate recurrent oncogenic driver alterations and dysregulated pathways in esophageal adenocarcinoma and to assess their prognostic value. EXPERIMENTAL DESIGN: We analyzed a large cohort of patients with lower esophageal and junctional adenocarcinoma, prospectively sequenced by MSK-IM...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Sihag, Smita, Nussenzweig, Samuel C., Walch, Henry S., Hsu, Meier, See Tan, Kay, Sanchez Vega, Francisco, Chatila, Walid K., De La Torre, Sergio, Patel, Assem, Janjigian, Yelena Y., Maron, Steven, Ku, Geoffrey Y., Tang, Laura H., Hechtman, Jaclyn, Shah, Pari M., Wu, Abraham, Jones, David R., Molena, Daniela, Solit, David B., Schultz, Nikolaus, Berger, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228505/
https://ncbi.nlm.nih.gov/pubmed/33795256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-4707
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