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Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin

The clinically highly relevant Clostridioides (C.) difficile releases several AB-type toxins that cause diseases such as diarrhea and pseudomembranous colitis. In addition to the main virulence factors Rho/Ras-glycosylating toxins TcdA and TcdB, hypervirulent strains produce the binary AB-type toxin...

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Bibliografiske detaljer
Udgivet i:Toxins (Basel)
Main Authors: Ernst, Katharina, Landenberger, Marc, Nieland, Julian, Nørgaard, Katharina, Frick, Manfred, Fois, Giorgio, Benz, Roland, Barth, Holger
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226936/
https://ncbi.nlm.nih.gov/pubmed/34071730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13060390
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