Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Integrase-Expressing Adenocarcinoma Cells

Therapeutic DNA-vaccination against drug-resistant HIV-1 may hinder emergence and spread of drug-resistant HIV-1, allowing for longer successful antiretroviral treatment (ART) up-to relief of ART. We designed DNA-vaccines against drug-resistant HIV-1 based on consensus clade A integrase (IN) resista...

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Published in:Microorganisms
Main Authors: Isaguliants, Maria, Krotova, Olga, Petkov, Stefan, Jansons, Juris, Bayurova, Ekaterina, Mezale, Dzeina, Fridrihsone, Ilze, Kilpelainen, Athina, Podschwadt, Philip, Agapkina, Yulia, Smirnova, Olga, Kostic, Linda, Saleem, Mina, Latyshev, Oleg, Eliseeva, Olesja, Malkova, Anastasia, Gorodnicheva, Tatiana, Wahren, Britta, Gordeychuk, Ilya, Starodubova, Elizaveta, Latanova, Anastasia
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226624/
https://ncbi.nlm.nih.gov/pubmed/34199989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9061219
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