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[β-Glu(2)]TRH Is a Functional Antagonist of Thyrotropin-Releasing Hormone (TRH) in the Rodent Brain

Selective antagonists of thyrotropin-releasing hormone (TRH; pGlu-His-Pro-NH(2)), in order to enable a better understanding of this peptide’s central functions, have not been identified. Using pGlu-Glu-Pro-NH(2) ([Glu(2)]TRH) as a lead peptide and with modification at its central residue, our studie...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Prokai-Tatrai, Katalin, Nguyen, Vien, Prokai, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226542/
https://ncbi.nlm.nih.gov/pubmed/34207724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126230
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