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Metal-binding effects of sirtuin inhibitor sirtinol

Sirtinol, a Schiff base derived from 2-hydroxy-1-naphthaldehyde, is an inhibitor of sirtuin proteins, a family of deacetylases active in gene regulation and relevant to the study of cancer growth. The formation of copper(II) and zinc(II) complexes of sirtinol is investigated by spectroscopic and str...

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Detalles Bibliográficos
Publicado en:Supramol Chem
Main Authors: Akam, Eman A., Gautam, Ritika, Tomat, Elisa
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225256/
https://ncbi.nlm.nih.gov/pubmed/34177214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10610278.2015.1092537
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