Mitochondrial Succinate Metabolism and Reactive Oxygen Species Are Important but Not Essential for Eliciting Carotid Body and Ventilatory Responses to Hypoxia in the Rat

Reflex increases in breathing in response to acute hypoxia are dependent on activation of the carotid body (CB)—A specialised peripheral chemoreceptor. Central to CB O(2)-sensing is their unique mitochondria but the link between mitochondrial inhibition and cellular stimulation is unresolved. The ob...

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Publicado en:Antioxidants (Basel)
Autores principales: Swiderska, Agnieszka, Coney, Andrew M., Alzahrani, Abdulaziz A., Aldossary, Hayyaf S., Batis, Nikolaos, Ray, Clare J., Kumar, Prem, Holmes, Andrew P.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225218/
https://ncbi.nlm.nih.gov/pubmed/34070267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10060840
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