Mitochondrial Succinate Metabolism and Reactive Oxygen Species Are Important but Not Essential for Eliciting Carotid Body and Ventilatory Responses to Hypoxia in the Rat

Reflex increases in breathing in response to acute hypoxia are dependent on activation of the carotid body (CB)—A specialised peripheral chemoreceptor. Central to CB O(2)-sensing is their unique mitochondria but the link between mitochondrial inhibition and cellular stimulation is unresolved. The ob...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Swiderska, Agnieszka, Coney, Andrew M., Alzahrani, Abdulaziz A., Aldossary, Hayyaf S., Batis, Nikolaos, Ray, Clare J., Kumar, Prem, Holmes, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225218/
https://ncbi.nlm.nih.gov/pubmed/34070267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10060840
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