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Development of Non-Ethoxypropanoic Acid Type Cryptochrome Inhibitors with Circadian Molecular Clock-Enhancing Activity by Bioisosteric Replacement

Circadian dysfunction is closely associated with an increased risk of various diseases. Considering that molecular clock machinery serves as an intrinsic time-keeping system underlying the circadian rhythm of biological processes, the modulation of the molecular clock machinery is an attractive ther...

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Foilsithe in:Pharmaceuticals (Basel)
Main Authors: Jeong, Yong Uk, Jin, Hyo-Eon, Lim, Hye Young, Choi, Goyeong, Joo, Hansol, Kang, Bohun, Lee, Ga-Hyun, Liu, Kwang-Hyeon, Maeng, Han-Joo, Chung, Sooyoung, Son, Gi Hoon, Jung, Jong-Wha
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225008/
https://ncbi.nlm.nih.gov/pubmed/34073760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14060496
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