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Rifampicin exposure reveals within-host Mycobacterium tuberculosis diversity in patients with delayed culture conversion

Mycobacterium tuberculosis (Mtb) genetic micro-diversity in clinical isolates may underline mycobacterial adaptation to tuberculosis (TB) infection and provide insights to anti-TB treatment response and emergence of resistance. Herein we followed within-host evolution of Mtb clinical isolates in two...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Genestet, Charlotte, Hodille, Elisabeth, Barbry, Alexia, Berland, Jean-Luc, Hoffmann, Jonathan, Westeel, Emilie, Bastian, Fabiola, Guichardant, Michel, Venner, Samuel, Lina, Gérard, Ginevra, Christophe, Ader, Florence, Goutelle, Sylvain, Dumitrescu, Oana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224949/
https://ncbi.nlm.nih.gov/pubmed/34166469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009643
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