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Diagnosis of Sickle Cell Disease and HBB Haplotyping in the Era of Personalized Medicine: Role of Next Generation Sequencing

Hemoglobin genotype and HBB haplotype are established genetic factors that modify the clinical phenotype in sickle cell disease (SCD). Current methods of establishing these two factors are cumbersome and/or prone to errors. The throughput capability of next generation sequencing (NGS) makes it ideal...

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Detaylı Bibliyografya
Yayımlandı:J Pers Med
Asıl Yazarlar: Adekile, Adekunle, Akbulut-Jeradi, Nagihan, Al Khaldi, Rasha, Fernandez, Maria Jinky, Sukumaran, Jalaja
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224627/
https://ncbi.nlm.nih.gov/pubmed/34071035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11060454
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