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Diagnosis of Sickle Cell Disease and HBB Haplotyping in the Era of Personalized Medicine: Role of Next Generation Sequencing

Hemoglobin genotype and HBB haplotype are established genetic factors that modify the clinical phenotype in sickle cell disease (SCD). Current methods of establishing these two factors are cumbersome and/or prone to errors. The throughput capability of next generation sequencing (NGS) makes it ideal...

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Detalhes bibliográficos
Publicado no:J Pers Med
Main Authors: Adekile, Adekunle, Akbulut-Jeradi, Nagihan, Al Khaldi, Rasha, Fernandez, Maria Jinky, Sukumaran, Jalaja
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224627/
https://ncbi.nlm.nih.gov/pubmed/34071035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11060454
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