Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes

The molecular composition and binding epitopes of the immunoglobulin G (IgG) antibodies that circulate in blood plasma following SARS-CoV-2 infection are unknown. Proteomic deconvolution of the IgG repertoire to the spike glycoprotein in convalescent subjects revealed that the response is directed p...

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Publicado no:Science
Main Authors: Voss, William N., Hou, Yixuan J., Johnson, Nicole V., Delidakis, George, Kim, Jin Eyun, Javanmardi, Kamyab, Horton, Andrew P., Bartzoka, Foteini, Paresi, Chelsea J., Tanno, Yuri, Chou, Chia-Wei, Abbasi, Shawn A., Pickens, Whitney, George, Katia, Boutz, Daniel R., Towers, Dalton M., McDaniel, Jonathan R., Billick, Daniel, Goike, Jule, Rowe, Lori, Batra, Dhwani, Pohl, Jan, Lee, Justin, Gangappa, Shivaprakash, Sambhara, Suryaprakash, Gadush, Michelle, Wang, Nianshuang, Person, Maria D., Iverson, Brent L., Gollihar, Jimmy D., Dye, John, Herbert, Andrew, Finkelstein, Ilya J., Baric, Ralph S., McLellan, Jason S., Georgiou, George, Lavinder, Jason J., Ippolito, Gregory C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224265/
https://ncbi.nlm.nih.gov/pubmed/33947773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg5268
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