Resident and circulating memory T cells persist for years in melanoma patients with durable responses to immunotherapy

While T-cell responses to cancer immunotherapy have been avidly studied, long-lived memory has been poorly characterized. In a cohort of metastatic melanoma survivors with exceptional responses to immunotherapy, we probed memory CD8(+) T-cell responses across tissues, and across several years. Singl...

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Bibliografski detalji
Izdano u:Nat Cancer
Glavni autori: Han, Jichang, Zhao, Yanding, Shirai, Keisuke, Molodtsov, Aleksey, Kolling, Fred W., Fisher, Jan L., Zhang, Peisheng, Yan, Shaofeng, Searles, Tyler G., Bader, Justin M., Gui, Jiang, Cheng, Chao, Ernstoff, Marc S., Turk, Mary Jo, Angeles, Christina V.
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223731/
https://ncbi.nlm.nih.gov/pubmed/34179824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-021-00180-1
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