FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS

Brain metastases are refractory to therapies that control systemic disease in patients with human epidermal growth factor receptor 2 (HER2+) breast cancer, and the brain microenvironment contributes to this therapy resistance. Nutrient availability can vary across tissues, therefore metabolic adapta...

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Detalhes bibliográficos
Publicado no:Nat Cancer
Main Authors: Ferraro, Gino B., Ali, Ahmed, Luengo, Alba, Kodack, David P., Deik, Amy, Abbott, Keene L., Bezwada, Divya, Blanc, Landry, Prideaux, Brendan, Jin, Xin, Possada, Jessica M., Chen, Jiang, Chin, Christopher R., Amoozgar, Zohreh, Ferreira, Raphael, Chen, Ivy, Naxerova, Kamila, Ng, Christopher, Westermark, Anna M., Duquette, Mark, Roberge, Sylvie, Lindeman, Neal I., Lyssiotis, Costas A., Nielsen, Jens, Housman, David E., Duda, Dan G., Brachtel, Elena, Golub, Todd R., Cantley, Lewis C., Asara, John M., Davidson, Shawn M., Fukumura, Dai, Dartois, Véronique A., Clish, Clary B., Jain, Rakesh K., Vander Heiden, Matthew G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223728/
https://ncbi.nlm.nih.gov/pubmed/34179825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-021-00183-y
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