Divanillyl sulfone suppresses NLRP3 inflammasome activation via inducing mitophagy to ameliorate chronic neuropathic pain in mice

BACKGROUND: Chronic neuropathic pain is a frequent sequel to peripheral nerve injury and maladaptive nervous system function. Divanillyl sulfone (DS), a novel structural derivative of 4,4′-dihydroxydibenzyl sulfoxide from a traditional Chinese medicine Gastrodia elata with anti-nociceptive effects,...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Shao, Shuai, Xu, Cheng-Bo, Chen, Cheng-Juan, Shi, Gao-Na, Guo, Qing-Lan, Zhou, Yu, Wei, Ya-Zi, Wu, Lei, Shi, Jian-Gong, Zhang, Tian-Tai
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223331/
https://ncbi.nlm.nih.gov/pubmed/34162415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02178-z
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