Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus

BACKGROUND: The potential mechanism of postoperative cognitive impairment is still largely unclear. The activation of NLRP3 inflammasome had been reported to be involved in neurodegenerative diseases, including postoperative cognitive change, and is closely related to mitochondrial ROS and mitophagy...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Ye, Ji-Shi, Chen, Lei, Lu, Ya-Yuan, Lei, Shao-Qing, Peng, Mian, Xia, Zhong-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409065/
https://ncbi.nlm.nih.gov/pubmed/30918581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8639618
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