Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus

BACKGROUND: The potential mechanism of postoperative cognitive impairment is still largely unclear. The activation of NLRP3 inflammasome had been reported to be involved in neurodegenerative diseases, including postoperative cognitive change, and is closely related to mitochondrial ROS and mitophagy...

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Bibliografische gegevens
Gepubliceerd in:Oxid Med Cell Longev
Hoofdauteurs: Ye, Ji-Shi, Chen, Lei, Lu, Ya-Yuan, Lei, Shao-Qing, Peng, Mian, Xia, Zhong-Yuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409065/
https://ncbi.nlm.nih.gov/pubmed/30918581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8639618
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