Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus

BACKGROUND: The potential mechanism of postoperative cognitive impairment is still largely unclear. The activation of NLRP3 inflammasome had been reported to be involved in neurodegenerative diseases, including postoperative cognitive change, and is closely related to mitochondrial ROS and mitophagy...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Ye, Ji-Shi, Chen, Lei, Lu, Ya-Yuan, Lei, Shao-Qing, Peng, Mian, Xia, Zhong-Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409065/
https://ncbi.nlm.nih.gov/pubmed/30918581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8639618
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