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Data Processing Thresholds for Abundance and Sparsity and Missed Biological Insights in an Untargeted Chemical Analysis of Blood Specimens for Exposomics

Background: An untargeted chemical analysis of bio-fluids provides semi-quantitative data for thousands of chemicals for expanding our understanding about relationships among metabolic pathways, diseases, phenotypes and exposures. During the processing of mass spectral and chromatography data, vario...

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Publicat a:Front Public Health
Autors principals: Barupal, Dinesh Kumar, Baygi, Sadjad Fakouri, Wright, Robert O., Arora, Manish
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222544/
https://ncbi.nlm.nih.gov/pubmed/34178917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpubh.2021.653599
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