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Variable Selection in Untargeted Metabolomics and the Danger of Sparsity

The goal of metabolomics is to measure as many metabolites as possible in order to capture biomarkers that may indicate disease mechanisms. Variable selection in chemometric methods can be divided into the following two groups: (1) sparse methods that find the minimal set of variables to discriminat...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Tinnevelt, Gerjen H., Engelke, Udo F.H., Wevers, Ron A., Veenhuis, Stefanie, Willemsen, Michel A., Coene, Karlien L.M., Kulkarni, Purva, Jansen, Jeroen J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698561/
https://ncbi.nlm.nih.gov/pubmed/33213095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo10110470
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